期刊简介

本刊的办刊方针为理论与实践相结合,提高与普及相结合,以宣传全面康复为宗旨,反映康复医学等方面的重大进展,促进学术交流。同时,不断增加社区康复内容。杂志以专题为特色,具有较好的可读性。

首页>中国康复理论与实践杂志
  • 杂志名称:中国康复理论与实践杂志
  • 主管单位:中国康复研究中心院刊;中国康复研究中心学刊
  • 主办单位:中国残疾人联合会
  • 国际刊号:11-3759/R
  • 国内刊号:11-3759/R
  • 出版周期:月刊
期刊荣誉:国家科技部中国科技论文统计源期刊期刊收录:国家图书馆馆藏, 维普收录(中), 万方收录(中), 上海图书馆馆藏, 北大核心期刊(中国人文社会科学核心期刊), 知网收录(中), CSCD 中国科学引文数据库来源期刊(含扩展版), 统计源核心期刊(中国科技论文核心期刊)
中国康复理论与实践杂志2002年第09期

关键词:polyamidoamine, gene delivery, transfection, review
摘要:Gene therapy recently has become an important area of research as a new therapeutic method. In vivo and in vitro gene therapies require efficient delivery of genetic material into a cell and preferably high levels of expression of transferred gene. Traditionally, gene delivery systems are classified as viral vector-mediated systems and nonviral vector-mediated systems. Viral vectors, which have been demonstrated as systems with high transfection efficiency, however, are limited due to adverse effects such as immunogenicity, toxicity, limited DNA carrying capacity and mutagenesis caused by cell-infected viruses[1].